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KMID : 1036520130030020074
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Clinical Neuro-Ophthalmology
2013 Volume.3 No. 2 p.74 ~ p.79
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Anti-GQ1b Antibody Syndro
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Kim Man-Young
Hur Wook
Choi Pahn-Kyu
Kim Dong-Uk
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Abstract
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Anti-GQ1b antibodies are commonly related to several neurological disorders including Fisher syndrome, Guillain?Barre syndrome with ophthalmoplegia, Bickerstaff brainstem encephalitis, acute ophthalmoplegia without ataxia, constituting a continuous spectrum. Surrounding this typical disease entity, anti-GQ1b positive patients displaying atypical central nervous system symptoms or variable central and peripheral involvement are reported. In this article, we review the concepts for classification, clinical considerations, pathogenesis, natural history and options for treatment of anti-GQ1b antibody syndrome.
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KEYWORD
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GQ1b ganglioside, Miller Fisher syndrome, Encephalitis, Guillain-Barre syndrome
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